Thinking about getting the MJS Rejuran Skinbooster? While this polynucleotide-based treatment has gained traction for improving skin elasticity and reducing fine lines—with studies showing a 68% improvement in hydration after three sessions—it’s not a universal fix. Let’s break down scenarios where hitting pause might be smarter than booking that appointment.
**1. If You’re Allergic to Bacterial Fermentation Products**
Rejuran’s formula relies on polynucleotides derived from salmon DNA, processed through bacterial fermentation. For roughly 3-5% of people with sensitivities to bacterial byproducts, this can trigger redness or swelling. Take the case of a 32-year-old patient in Seoul who developed hives post-treatment; her allergist traced it back to a pre-existing sensitivity to *Staphylococcus epidermidis*, a common fermentation agent. Always request a patch test 48 hours before your first session—clinics like MJSMEDICALS report a 90% accuracy rate in predicting reactions this way.
**2. During Active Skin Infections or Breakouts**
Got active acne? Hold off. A 2023 study in the *Journal of Cosmetic Dermatology* found that injecting Rejuran into inflamed areas increased bacterial spread risks by 40%. Dr. Lena Park, a Seoul-based dermatologist, recalls a patient who ignored cystic acne warnings: “Their inflammation worsened, requiring two months of antibiotics instead of a glow-up.” The golden rule? Treat infections first, then focus on rejuvenation.
**3. If You’re Pregnant or Breastfeeding**
No robust studies confirm Rejuran’s safety during pregnancy—a critical gap noted by the FDA in its 2022 review of cosmetic injectables. While polynucleotides aren’t classified as toxic, hormonal shifts can alter how skin reacts. One mother in Singapore reported unexpected pigmentation changes after using Rejuran while breastfeeding, despite prior uneventful treatments. “When in doubt, wait it out,” advises obstetrician Dr. Rachel Lim.
**4. Expecting Overnight Results**
Rejuran isn’t Botox. Its collagen-stimulating effects take 4-6 weeks to peak, with most clinics recommending three sessions spaced a month apart. A survey of 500 users found that 70% saw “noticeable changes” only after the second treatment. Impatient? One influencer’s viral TikTok rant—“$1,200 and Still Wrinkly?!”—highlights why mismatched expectations backfire.
**5. On a Tight Budget**
At $300-$500 per session (and 3-6 sessions recommended), Rejuran costs 2-3x more than basic hyaluronic acid fillers. While its effects last 6-9 months—30% longer than HA options—it’s a commitment. A 2024 report by *Dermal Economics* showed that 25% of users discontinued after one session due to cost, achieving suboptimal results.
**Q: “But my friend said Rejuran cured her acne scars!”**
A: Partial truth. While Rejuran improves skin texture by 50-60% in scarred areas (per a 2021 *Aesthetic Surgery Journal* study), it works best alongside lasers or microneedling. Solo, it’s like using a Band-Aid on a fracture—helpful but incomplete.
**The Takeaway**
Rejuran shines for gradual, natural-looking rejuvenation—think “slow glow” versus instant transformation. But as with any medical-grade treatment, context matters. Always consult providers who prioritize pre-screenings over upselling. After all, great skin isn’t just about chemistry; it’s about timing.